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Cursus: NWI-BB086
NWI-BB086
Genomics for Health and Environment
Cursus informatieRooster
CursusNWI-BB086
Studiepunten (ECTS)12
CategorieBA (Bachelor)
VoertaalEngels
Aangeboden doorRadboud Universiteit; Faculteit der Natuurwetenschappen, Wiskunde en Informatica; BioWetenschappen;
Docenten
Coördinator
dr. C. Logie
Overige cursussen docent
Docent
dr. C. Logie
Overige cursussen docent
Contactpersoon van de cursus
dr. C. Logie
Overige cursussen docent
Collegejaar2016
Periode
KW1  (29-08-2016 t/m 06-11-2016)
Aanvangsblok
KW1
Onderwijsvorm
voltijd
Opmerking-
Inschrijven via OSIRISJa
Inschrijven voor bijvakkersJa
VoorinschrijvingJa
Voorinschrijving geopendvanaf - t/m -
WachtlijstJa
PlaatsingsprocedureHandmatig door Administratie
ToelichtingHandmatig door Administratie
Cursusdoelen

Learning outcomes: At the end of the course you can:

  • conduct nucleic acid isolation and library preparation for the major next-generation DNA sequencing machines in a small team 
  • use the Bash shell to navigate directory structures, manipulate files and execute commands in an automated manner
  • identify functionally relevant genetic variation in genes
  • define the human microbiome and explain the role metagenomics plays in its investigation
  • define the transcriptome and explore its features
  • define human genetic variation
  • explore metabolic and signal transduction pathways
  • report on your next generation sequencing research findings in a public talk
  • reflect on ethical questions and implications pertaining to next generation sequencing applications in medicine and ecology.
Inhoud

The general objective is to provide students with theoretical background and hands-on experience in microbial (meta)genomics, medical genomics and transcriptomics.  Bioinformatic aspects of genome complexity, read mapping, next generation DNA sequencing (NGS) signal quantification and functional interpretation are taught.

There is a 3 week long department-specific full time practical component to this course, split across the Microbiology (FNWI), Human  Genetics (UMCN) and Molecular Biology (FNWI) departments. During this practical you will perform research in groups of 3 students together with researchers from one of the departments, working with them on their ongoing research topic. Hence GHE students are exposed to state-of-the-art research practice. Students from each practical group report their findings during a two-day symposium which also hosts international speakers.

Bijzonderheden
This course will be taught in English
Onderwerpen
• Metagenomics
• Human genomics
• Transcriptomics
Toetsinformatie
The final mark is determined for 50% by the final exam, 40% for the practical work and symposium and for 10% by the essay.
Voorkennis
Required for biology students: Molecular Biology I (BP010B) and Geomicrobiology of Microorganisms (BP029B)Prefered for all students: Advanced Molecular Biology (BB064B (BMBII) or equivalent)For 2016, participation is limited to 45 students who must register personally through the course coordinator (clogie@science.ru.nl).
Literatuur
Lecture power points, working group hand-outs and practical protocols will be provided on site and via Blackboard.
Werkvormen

• 22 hours guided individual project work
• 45 hours computer course
• 41 hours lecture
• 78 hours laboratory course
• 12 hours student presentation
• 2 hours question session
• 20 hours tutor session
• 2 hours problem session
• 114 hours individual study period
Aanbevolen materiaal
Blackboard
Lecture power points, working group hand-outs and practical protocols will be provided on site and via Blackboard.
Werkvormen
Computerpracticum
AanwezigheidsplichtJa

Cursus
AanwezigheidsplichtJa

Practicum
AanwezigheidsplichtJa

Presentatie
AanwezigheidsplichtJa

Project
AanwezigheidsplichtJa

Responsiecollege

Werkcollege

Zelfstudie
AanwezigheidsplichtJa

Toetsen
Tentamen
Weging1
GelegenhedenBlok KW1, Blok KW2

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