After this course, you're able to:
1. infer the effects of genome variation, such as polymorphisms, mutations, and copy number variations, on human diversity.
2. describe the strengths and weaknesses of the different techniques to study the human genome and can apply these techniques according to the specific research question at hand.
3. infer the (non)Mendelian inheritance pattern of a disease based upon family anamnesis and calculate the recurrence risk.
4. describe the complex interaction between heritability and environment resulting in common multifactorial diseases.
5. predict the effect of genetic factors on the efficacy of medication.
6. write an argumentative, well-organized short essay on a contemporary ethical human genetics subject.
New powerful genome-wide techniques have instigated a new era in human genetic research and DNA diagnostics. Only 10 years ago, it was thought that the human genome was mostly invariable and differences between individuals small. Now we know that even relatively large pieces of DNA may be missing without severe consequences for the individual in question. This genomic variation has major implications for our own lives, as it influences intelligence, longevity, strength, speed, and much much more.
In this course, we will discuss the latest developments in human genetics and its consequences for daily life; from super(wo)man to patient.