SluitenHelpPrint
Switch to English
Cursus: NWI-BM064
NWI-BM064
Protein Dynamics and Networks
Cursus informatieRooster
CursusNWI-BM064
Studiepunten (ECTS)3
CategorieMA (Master)
VoertaalEngels
Aangeboden doorRadboud Universiteit; Faculteit der Natuurwetenschappen, Wiskunde en Informatica; BioWetenschappen;
Docenten
Coördinator
prof. dr. M. Vermeulen
Overige cursussen docent
Docent
prof. dr. M. Vermeulen
Overige cursussen docent
Docent
dr. N.C. Vermeulen
Overige cursussen docent
Contactpersoon van de cursus
prof. dr. M. Vermeulen
Overige cursussen docent
Collegejaar2016
Periode
KW1  (29-08-2016 t/m 06-11-2016)
Aanvangsblok
KW1
Onderwijsvorm
voltijd
Opmerking-
Inschrijven via OSIRISJa
Inschrijven voor bijvakkersJa
VoorinschrijvingNee
WachtlijstNee
Plaatsingsprocedure-
Cursusdoelen

At the end of the course you can:

·         Understand the common principles used in quantitative mass spectrometry (MS)-based proteomics and apply this knowledge to address questions in data-driven research (P1, P2).

·         Independently perform and analyze MS-based protein pull-downs to investigate protein-protein interactions (P3).

·         Evaluate and interpret recent literature about protein dynamics and networks and apply this knowledge to address new research questions (P4).

·         Judge and discuss ongoing research from guest speakers, thus demonstrating acquired knowledge in state-of-the-art proteomics research (A1, A2).

·         Acknowledge the complementary nature of proteomics and (epi-)genomics approaches and design simple approaches to study relevant questions on a system-wide level (P5)

Inhoud
This course aims to present the current state-of-the-art in proteomics, in particular in the context of epigenetics research (heritable modifications of chromosomes). Special emphasis will be given to applications in health and disease, such as development and cancer. The course will consist of lectures, seminars from external academic and industrial experts as well as a practical component.
Onderwerpen
• Basic principles and workflows of quantitative mass spectrometry
• Signaling pathways / post-translational modifications
• Protein-protein and protein-DNA interactions
• Proteomics in epigenetics research
• Protein (complex) structures
• Clinical proteomics
• Applied mass spectrometry in industry
• Integrative proteomics for systems biology
Toetsinformatie
written exam (70%), practical report (20%), Q+A session (10%)
Voorkennis
Knowledge of the principles of genome architecture and gene regulation (NWI-BB064B (Functional Genomics I) or Lodish 7th edition chpt 5-7 or equivalent)
Werkvormen

• 12 hours guided group project work
• 2 hours excursion
• 15 hours lecture
• 10 hours laboratory course
• 3 hours question session
• 2 hours tutor session
• 40 hours individual study period
Extra information teaching methods: lectures, pracitcal, guest lectures, study current literature, Q+A session, excursion
Werkvormen
Cursus
AanwezigheidsplichtJa

Hoorcollege

Practicum
AanwezigheidsplichtJa

Project
AanwezigheidsplichtJa

Responsiecollege

Werkcollege
AanwezigheidsplichtJa

Zelfstudie

Toetsen
Tentamen
Weging1
GelegenhedenBlok KW1, Blok KW2

SluitenHelpPrint
Switch to English