At the end of the course you can:
· Understand the common principles used in quantitative mass spectrometry (MS)-based proteomics and apply this knowledge to address questions in data-driven research (P1, P2).
· Independently perform and analyze MS-based protein pull-downs to investigate protein-protein interactions (P3).
· Evaluate and interpret recent literature about protein dynamics and networks and apply this knowledge to address new research questions (P4).
· Judge and discuss ongoing research from guest speakers, thus demonstrating acquired knowledge in state-of-the-art proteomics research (A1, A2).
· Acknowledge the complementary nature of proteomics and (epi-)genomics approaches and design simple approaches to study relevant questions on a system-wide level (P5)
|This course aims to present the current state-of-the-art in proteomics, in particular in the context of epigenetics research (heritable modifications of chromosomes). Special emphasis will be given to applications in health and disease, such as development and cancer. The course will consist of lectures, seminars from external academic and industrial experts as well as a practical component.|