At the end of this course, you will be familiar with the biomedical significance of metabolites and biomolecules in molecular life sciences. Emphasis will be put on integration of compounds in the larger cellular network associated with metabolism, transport and motility under physiological and pathological conditions.
At the end of the course, you are able to:
- appreciate the significance of ‘metabolic, transport and motion research’ in molecular life sciences
- and medicine
- describe molecular mechanisms in pathologic conditions
- use modern technologies to design and study molecular therapeutic strategies
- implement the newly obtained knowledge to design future applied and fundamental research
You will be offered a comprehensive series of lectures on specific subjects in the field of molecular life sciences that go beyond basic (bachelor) knowledge of biochemistry and cell biology. You will read background literature and make yourself familiar with the significance of membrane transporters in drug disposition, metabolite profile analysis, water and electrolyte transport, mobility control, molecular pathology of trinucleotide disease involving intracellular processing and transport of RNA and protein.
These topics will be discussed in the context of multifactorial and multisystemic disorders, such as chronic kidney disease, Alzheimers disease, myotonic dystrophy, channelopathies, P-type ATPase related diseases. The value of multi-disciplinary approaches and state-of-the-art research methodologies will be discussed.