| At the end of the course you are able to:
- describe general molecular and cellular principles of biotechnology
- describe the application of biotechnology to prevent, diagnose or treat human disease
- identify recent developments in medical biotechnology
- design new strategies to use medical biotechnology in clinical practice
- recognize and evaluate ethical, regulatory and societal aspects of biotechnology in medicine
- work and collaborate effectively in a group
- effectively communicate scientific information orally and in writing
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| Medical biotechnology is the application of living cells or cell material in the development or generation of products to prevent, diagnose or treat human disease. Historical examples of biotechnology in support of medicine are the development of vaccines against smallpox and the production of antibiotics or human insulin by bacteria or yeast. Exciting 21st century developments are genetic engineering, gene therapy and stem cell-based regenerative medicine. Medical biotechnology is a rapidly evolving field integrating knowledge obtained in molecular, cell biological, genetic and immunological scientific areas.
Through this course, you will obtain an overview of how interdisciplinary efforts help shaping modern healthcare by developing biotechnological diagnostics and therapeutics for precision medicine. Principles and concepts of medical biotechnology will be discussed in a scientific and societal context, including ethical and legal considerations. Together with fellow-students you will use this knowledge and write a medical biotechnological research proposal and present this during a mini-symposium. Medical Biotechnology towards Clinical Practice presents an excellent foundation for students interested in molecular life sciences in relation to modern clinical practice.
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 NWI-MOL104 is identical to the first half of the (Radboudumc) minor MED-MIN13 for Biomedical Sciences students. Maximally 24 BMS students will be admitted to this minor. This means that at least 24 (and maximally 48) slots are available for Molecular Life Sciences and (Medical) Biology students. Application deadline is July 31, 2016.In case the number of applications exceeds the available positions, a selection will be made by the coordinators in August 2016. Selection will be based on motivation.Therefore, FNWI students are invited to send a letter of motivation to the coordinators before August 1, 2016. |
• Advanced cloning, engineering and genetic modification • Antibodies, vaccines, immunotherapy • Gene therapy and genetic therapy • Stem cell therapy and regenerative medicine • Ethical, legal, economical and societal perspectives |
Assessment consists of four parts (each must be graded at least 5.5 to pass the course): • Written exam (individual; total weight 40%) • Written mini-review and research proposal (group; weight 40%) • Oral presentation of research proposal (group; weight 10%) • Performance, initiative, input and participation during the course (individual; weight 10%) |
This is a course in the programme 'Molecular life sciences'.Knowledge obtained in the courses “Celbiologie der Dieren” and “Biochemie & Moleculaire Biologie II” is required.In view of the maximal number of students that can be dealt with in the course, a selection procedure may be conducted (see Extra information below). |
• Lodish et al., Molecular Cell Biology, 7th ed., McMillan Higher Education/ W.H.Freeman & Company, ISBN 1-4641-0981-8; • Nelson & Cox , Lehninger Principles of Biochemistry, 6th ed., Macmillan , ISBN-13: 9781464109621, • Griffiths et al., Introduction to Genetic Analysis, 10th ed., ISBN-13: 978-1-4292-7634-4 • Abbas et al., Cellular and Molecular Immunology, 7th ed., ISBN: 978-1-4377-1528-6 • Literature and additional material provided via Blackboard |
• 6 hours computer course • 22 hours lecture • 48 hours group project work without guidance • 4 hours student presentation • 11 hours question session • 5 hours tutor session • 60 hours individual study period Extra information teaching methods: The course language is English. |
| | Verplicht materiaalBoekLodish et al., Molecular Cell Biology, 7th ed., McMillan Higher Education/ W.H.Freeman & Company |
 | BoekNelson & Cox , Lehninger Principles of Biochemistry, 6th ed., Macmillan |
ISBN | : |  | 9781464109621 |
 | BoekGriffiths et al., Introduction to Genetic Analysis, 10th ed |
ISBN | : |  | 9781429276344 |
 | BoekAbbas et al., Cellular and Molecular Immunology, 7th ed |
ISBN | : |  | 9781437715286 |
 | BlackboardLiterature and additional material provided via Blackboard |
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| Werkvormen Computerpracticum 
 | Cursus 
 | Hoorcollege 
 | Presentatie Aanwezigheidsplicht |  | Ja |

 | Project Aanwezigheidsplicht |  | Ja |

 | Responsiecollege 
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| Toetsen TentamenWeging |  | 1 |
Gelegenheden |  | Blok KW1, Blok KW3 |
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