After successfully completing the course you will:
- know the roots of the theoretical background behind the magnetic resonance phenomenon
- be familiar with a number of 1D and 2D NMR experiments relevant to synthetic chemistry labs
- be able use 1D and 2D NMR spectra to elucidate molecular structures
- have gained some basic understanding of NMR spectrometer operation.
Magnetic resonance techniques have a broad range of application in chemistry, physics, life sciences, materials science and medicine. This course covers the basics of magnetic resonance spectroscopy and will describe its applications relevant to the chemistry lab. First, the theoretical framework of magnetic resonance is covered in the lectures using the vector model. The chemical shift, J-coupling and multiplet structure is described. Spectral editing techniques and 2D NMR experiments that are used for structure elucidation in addition to dynamical effects such as chemical exchange will all help the student to use NMR as a tool in their future research.
- Magnetisation and spin angular momentum
- T1 and T2 Relaxation
- Spectrometer operation and data processing
- NMR interactions
- Chemical shift
- Decoupling and spectral editing techniques
- 2D NMR (COSY, HSQC, NOESY)
- Dynamical processes.