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Cursus: NWI-MOL403
NWI-MOL403
Organic Chemistry of Biomolecules
Cursus informatieRooster
CursusNWI-MOL403
Studiepunten (ECTS)3
CategorieMA (Master)
VoertaalEngels
Aangeboden doorRadboud Universiteit; Faculteit der Natuurwetenschappen, Wiskunde en Informatica; Moleculaire Wetenschappen;
Docenten
Docent
dr. T.J. Boltje
Overige cursussen docent
Docent
D.W.P.M. Löwik
Overige cursussen docent
Coördinator
D.W.P.M. Löwik
Overige cursussen docent
Contactpersoon van de cursus
D.W.P.M. Löwik
Overige cursussen docent
Collegejaar2016
Periode
KW1  (29-08-2016 t/m 06-11-2016)
Aanvangsblok
KW1
Onderwijsvorm
voltijd
Opmerking-
Inschrijven via OSIRISJa
Inschrijven voor bijvakkersJa
VoorinschrijvingNee
WachtlijstNee
Plaatsingsprocedure-
Cursusdoelen
  • Be able to apply naming conventions
  • Be able to apply protective groups in an organic synthesis
  • Be aware of the main concerns synthesizing biomolecules
  • Have knowledge of the chemistry required to plan a synthesis of peptides, carbohydrates and DNA
  • Make a motivated choice between a solid phase and solution phase strategy
  • Devise a chemical (semi)-synthesis of a large protein
  • Understand how to introduce selective modifications and construct conjugates of biomolecules
Inhoud
This course aims to provide an organic chemistry basis for the track Chemical Biology but is open to all Chemistry and MLW students. The student is provided with a broader look on the organic chemistry of bio-molecules. In addition to the chemical synthesis of peptides/proteins, carbohydrates and DNA/RNA topics like protective group strategy, solid phase chemistry, chemoselective modifications and conjugation chemistry will be covered as well as some structural and analytical aspects.
Onderwerpen
• chemical synthesis of peptides/proteins
• carbohydrates
• DNA/RNA
• protective group strategy
• solid phase chemistry
• chemoselective modifications
• conjugation chemistry
• structure and analysis of biomolecules
Toetsinformatie
written exam
Voorkennis
Bachelor SK/MLW (preferably Atoom- en Molecuulbouw (NWI-MOL079), Moleculaire structuur (NWI-MOL080), Reacties en Kinetiek (NWI-MOL007), Biomoleculen (NWI-MOL008), Synthese biomoleculen (NWI-MOL047), Organische chemie (NWI-MOL095))This is a mandatory course in the specialisation 'Chemistry for Life'.
Literatuur

• handouts and syllabus
Recommended:

• B. G. Davis and A.J. Fairbanks, Oxford Chemistry primers, Carbohydrate Chemistry, Oxford University Press;
• J. Jones, Oxford Chemistry primers, Amino Acid and Peptide Synthesis, Oxford University Press
Werkvormen

• 32 hours lecture
• 52 hours individual study period
Verplicht materiaal
Dictaat
Handouts and Syllabus
Boek
B. G. Davis and A.J. Fairbanks, Oxford Chemistry primers, Carbohydrate Chemistry, Oxford University Press
Boek
J. Jones, Oxford Chemistry primers, Amino Acid and Peptide Synthesis, Oxford University Press
Werkvormen
Hoorcollege

Werkcollege

Zelfstudie

Toetsen
Tentamen
Weging1
ToetsvormTentamen
GelegenhedenBlok KW1, Blok KW2

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