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Course module: NWI-BM065
NWI-BM065
Microbial Cell Structure & Function
Course infoSchedule
Course moduleNWI-BM065
Credits (ECTS)3
CategoryMA (Master)
Language of instructionEnglish
Offered byRadboud University; Faculty of Science; BioWetenschappen;
Lecturer(s)
Coordinator
dr. M.I. De Jonge
Other course modules lecturer
Lecturer
dr. M.I. De Jonge
Other course modules lecturer
Contactperson for the course
dr. M.I. De Jonge
Other course modules lecturer
Lecturer
dr. S. van Selm
Other course modules lecturer
Academic year2017
Period
KW1  (04/09/2017 to 12/11/2017)
Starting block
KW1
Course mode
full-time
Remarks-
Registration using OSIRISYes
Course open to students from other facultiesYes
Pre-registrationNo
Waiting listNo
Placement procedure-
Aims
  • Student is able to critically analyze and discuss current concepts and understanding of microbial cell structure and function
  • Student is able to explain how unique bacterial structures  can be used as targets for vaccines and antimicrobial compounds and is able to design strategies to develop new antibiotics and vaccines
  • Student understands different aspects of bacterial genetics and is able to translate the consequences of genetic variation on drug resistance and vaccine escape
  • Student is able to identify differences in microbial cell membrane and cell wall structures of Gram-positive and Gram-negative bacteria and has knowledge on membrane transport and on biosynthesis of cell membrane and cell wall structures
  • Student is able to summarize the different phases and categorize the different cell structures involved in cell division
  • Student is able to describe mechanisms of bacterial communication and motility
Content

Microbes have developed ingenious mechanisms to survive and propagate in different environments. The focus of the topic is on the molecular basis of essential physiological processes such as gene expression, cell division, protein secretion and cell wall synthesis and the molecular mechanisms that are employed to acquire nutrients, to move, to communicate and to attach to different surfaces. Furthermore, we will elaborate on the background of advanced biochemical, biophysical and molecular genetic methods and techniques that are used to discover the molecular world of microbes.

Literature
Brock Biology of Microorganisms, 14th edition, Pearson, chapter 2, 4, 5 (part I), 7 (part III)
Teaching formats

• 10 hours lecture
• 20 hours question session
• 20 hours problem session
• 34 hours individual study period
Additional comments
The course is a mandatory course within the MSc Biology specialisation Microbiology. The number of places is limited to allow for six additional students from other study programs. Please inquire with the course coordinator Dr. Marien de Jonge.(Marien.DeJonge@radboudumc.nl).
Topics
• Microbial genetics
• Microbial cell membrane and cell wall structures
• Cell division
• Bacterial communication and motility
• Application of knowledge on microbial cell structure and function
Test information
Written examination (75%) and self study assignment (research proposal) + presentation (25%)
Prerequisites
Basic knowledge in microbial physiology and biochemistry as can be obtained in the course "Physiology of Microorganisms" in the BSc Biology at RU or by self-study with the books "Brock Microbiology of Microorganisms" and "Stryer: Biochemistry"
Required materials
Book
Brock Biology of Microorganisms, 14th edition, Pearson, chapter 2, 4, 5 (part I), 7 (part III)
ISBN:9780321897398
Instructional modes
Course
Attendance MandatoryYes

Lecture

Working group

Zelfstudie

Tests
Tentamen
Test weight1
OpportunitiesBlock KW1, Block KW2

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